The chemical imbalance theory of depression is dead, but that doesn’t mean antidepressants don’t work Editors' Picks The death of the chemical imbalance theory has no bearing on whether antidepressants that affect the serotonin system are effective.
Depression is probably not caused by a chemical imbalance in the brain, new study July 22, 2022 By Joanna Moncrieff and Mark Horowitz Editors' Picks A new study shows there’s no clear evidence that depression is caused by abnormally low levels of serotonin in the brain.
